Functional Analysis of Human MUC7 Mucin Gene 5′-Flanking Region in Lung Epithelial Cells
نویسندگان
چکیده
منابع مشابه
Functional analysis of human MUC7 mucin gene 5'-flanking region in lung epithelial cells.
The human MUC7 gene encodes a low-molecular-mass mucin glycoprotein that functions in modulation of microbial flora in the oral cavity and respiratory tracts. MUC7 gene expression is tissue- and cell-specific, with dominant expression in salivary gland acinar cells. To begin to understand the molecular mechanisms responsible for controlling MUC7 gene expression, we analyzed the promoter activit...
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OBJECTIVE The human MUC7 gene encodes a low-molecular-weight mucin glycoprotein that functions in lubrication/protection of epithelial surfaces of the oral cavity and respiratory tract. This study was designed to evaluate the effect of cigarette smoke extract (CSE), cigarette smoke (CS), and Pseudomonas aeruginosa lipopolysaccharide (LPS), either alone or in the combination, on MUC7 expression ...
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ژورنال
عنوان ژورنال: American Journal of Respiratory Cell and Molecular Biology
سال: 2006
ISSN: 1044-1549,1535-4989
DOI: 10.1165/rcmb.2006-0110oc